Tag Archives: General

Sample Essay on Self-esteem

The following is an essay about self-esteem and the benefits and negative consequences it may have on one’s life. Everyone can use this according to their need. Necessary changes can be done.

Sample Essay on Self-esteem

The word self-esteem is used in psychology to define a person’s total subjective feeling of personal worth or value. In other terms, self-esteem may be described as how much you like and value yourself regardless of your circumstances. Many elements contribute to your self-esteem, including self-confidence, a feeling of security, identity, a feeling of connection, and a feeling of achievement. Having healthy self-esteem may affect your motivation, mental health, and general quality of life. However, possessing either too high or very low self-esteem might be harmful. Understanding your own degree of self-esteem can assist you in striking the ideal balance for you.

Self-esteem is not the same as self-concept, but it may be a component of self-concept. Self-concept is our image of ourselves, our answer to the question “who am I, exactly?” It involves being aware of one’s own inclinations, ideas, tastes, and habits, as well as one’s own interests, abilities, and areas of weakness. Certain criteria distinguish how high a person’s self-esteem is. Being open to criticism, admitting mistakes, being comfortable with giving and accepting praises, and demonstrating harmony between what one speaks, performs, sees, hears, and moves are examples of these traits. People with strong self-esteem are not hesitant to express their interests and share their experiences, thoughts, and possibilities. They can also appreciate the funny elements of their lives and are at ease with social or personal assertiveness. Although low self-esteem has gotten more attention than high self-esteem, the positive thinking trend has pushed high self-esteem to the forefront. Low self-esteem can lead to or be a sign of mental health problems such as anxiety and depression.

Though certain causes of low self-esteem, such as hereditary characteristics, early childhood events, and personality features, cannot be changed, there are actions you can do to feel safer and appreciated. Remember that no one individual is less deserving than another. Keeping this in mind may aid in the maintenance of a good sense of self-esteem.

EASY Urgent Leave Messages

These messages can be used by employees for urgent leave approval due to different reasons. Just change the information where and as required according to need.

Easy urgent leave messages

Urgent Leave Message Due To Throat Infection.

Hi,

I am Sana Khan working in the production department. It is to notify you that I have a throat infection, due to which I will not be able to come today. Kindly grant me leave for today.

Thanks.

Urgent Leave Message Due To Leg Injury.

Hi,

It is to notify you that I got an injury in my left leg as I fell off stairs. Due to this, I will not be able to join you for work today. Kindly grant me leave.

Thanks.

Urgent Leave Message Due To Surgery.

Dear Sir,

It is to request you to grant me an urgent 3-day leave as my surgery date with the doctor got fixed for tomorrow. I have a minor surgery will join you soon.

Thanks.

Name: (yours)

Urgent Leave Message Due To Eye Infection.

Dear Sir,

I need an urgent leave for today as I woke up with an eye infection out of a sudden so will not be able to come today. I hope it will get better by tomorrow and I will join.

Name: (yours)

Thanks.

Urgent Leave Message Due To Sick Kid.

Respected Sir,

It is to request you to allow me a leave for today as my youngest kid has a fever and needs to be taken to the hospital. I hope he will get better soon and I will join you tomorrow.

Will be thankful.

Ali Tareen.

Urgent Leave Message Due To Urgent Delivery

Hi,

It is to request you to allow me to have a leave for today as I have a very important parcel coming today and I need to collect it myself. Will get back to work by tomorrow.

Thanks.

Rubab khan.

Urgent Leave Message Due To Doctor Appointment.

Dear Sir,

I have an appointment with my doctor today regarding my health issues I will be very thankful if you allow me a leave for today as I can’t miss it.

Thank.

Nasir Ali.

Urgent Leave Message Due To Death Of  Close Family Member.

Respected ma’am,

I will not be able to come to work today as my very dear and only aunt passed away today morning. Being very close to her I can’t miss her funeral and need time to recover from my loss. Kindly, allow me a leave for today.

Thanks, Name: (yours).

Sample Notice of the Inability to Ship

We are writing to inform you about the failed shipment attempt. The parcel has not been received by anyone and is thus returned to our regional office. Kindly cooperate with us and provide us with updated information so we can provide you with our services on time.

Sample Notice of the Inability to Ship

Dear customer, 

This is to inform you that your package was not delivered to the address mentioned. Your parcel left our regional office on October 29, 2020. The delivery person reached the mentioned building and waited for the residents to show up at the door. He waited for a long-time but no one was present at the shipping address. Thus, it was not delivered. We believe that it is our responsibility to inform you of this issue and make arrangements for another delivery attempt. You can contact our regional office for another shipment or visit the nearest branch. We would also recommend you inform the receiving party to be aware of this delivery. If the package is not delivered this time, it will be returned to your address. Your tracking number and other delivery details file is attached. Thank you for your patience and cooperation. 

Sample Notice of Inability to Ship

Dear customer, 

We are writing this to inform you of the failed shipment attempt. Your parcel was received at our office on October 26, 2020. The parcel left our office on October 28, 2020, at 2 p.m. Our delivery person reached your provided address to find that it was the wrong address. The residents of the house and the neighbors confirmed that no such person lives in or near the address provided. We would like to request you to contact our office or visit the nearest office to change the shipment information. We would suggest you do it in three working days. In case you cannot manage to do this, we will deliver the parcel to your address. Kindly cooperate with us in this matter so we can arrange redelivery and provide you the best services. We will be waiting for your prompt response. Thank you.

Best Ten Tips to Spend Time during Quarantine

Best Ten Tips to Spend Time during Quarantine

Quarantine surely confines your outgoing and lifestyles are affected when less opportunities pop up. Its really hard to spend time doing something productive in quarantine. Following are best ten tips to spend
time during quarantine:

  1. Take Masterclass for the course you always wanted to do but never got a time for it. It is the best time to spend working on things you wanted to do for a long time.
  2. Be a pro-chef! Learn how to do cooking. Make some delicious food with the help of YouTube videos and your mum around in quarantine. Serve everyone yummiest food ever.
  3. Keep yourself active! Don’t rely on munchies. Even if gyms are closed, workout at your home and be physically fit. You can take virtual classes by your instructor while quarantined. This will also make you habitual of working out from home. It is one of the best tip to spend time during quarantine.
  4. Work on your passion. The passion you always had but never got a chance to be excel on it. This is the right time to work on it and be the master of all skills.
  5. Start writing journal. This journal will help you make record of all of the historical moments you are witnessing during quarantine.
  6. Start eating healthy. One of the best tips you can adopt in this quarantine is start eating greener. Fortify your immune system with all the greens. Keep yourself healthy and support your immune system with veggies.
  7. Try to spend your time in quarantine by learning about world, politics and climate change. Explore about international and national tourism. Enhance your knowledge and be a little wiser in this quarantine.
  8. Awake the artist in you. Create some quarantine masterpiece. Utilize the time by spending it on creating an art that you are going to preserve and cherish for whole of your life. Painting is a great way to spend time and be productive at same time. Take the inspiration from surrounding or channel your ideas into your art.
  9. Quarantine can be little too hard on your mind sometime. So, it is okay to do something fun for yourself too. Watch your favorite season and have some fun time. This is one of the best tips during quarantine for your mind to freshen up and be functional.
  10. Read a happy book. Reading is important, it opens your mind and make you feel a lot of stuff at same time.

Modern Science Impact on Students

Modern Science Impact on Students 

Science affects us all in one way or another. Modern science is taking over the world gradually. Quest for modern science knowledge is indeed a spell. Science always amazes students with its discoveries and products. Students of this century are exploring every palace of science and improvising things at their best. It is important for students to learn about Modern Science. Genomics, Cancer Research, Biotechnology impacts on science and how it is the traditional science. The scientific community generates journal and publish research paper and doing impeccable amount of work is the prove that science has reached its new heights.

People are interested to know how chemistry between chemicals occur, which chemical will react with other and what would it form? would it be helpful for the mankind or destructive. there is no doubt that science has created destructive and catastrophe things but it has also given us immunity from so many diseases. Vaccines and antibiotics are the reason that scientists researched more when traditional ways failed. Phage therapy is now abundantly used instead of antibiotics. People with several diseases are being treated by it and leading a healthy life. Cancer is now treated by chemotherapy, radiation therapy and hormone therapy.
Bioinformatics has brought new change in the research world. In silico work is helping tons of researchers and students in their in vitro lab work. They are conducting in silico researches prior to in vitro work. Government need to trust students with advance science and invest in young minds. Modern science has no boundaries, its craze is rising day by day. People are changing genders and turning into a new identity is all hail to modern science.

By exploring human body to no end, people are now able to come out as different orientation and undergo various kind of surgeries to change themselves physically. Modern Science has given the chance to childless parents to bear a child. Surrogacy, In vitro fertilization has made it easy for people to have their own child even if they are unable to bear it by themselves. This is modern science which is knocking off the genes and silencing the mutated and deleterious gene so disease can be cured. Mutations can be predicted easily now. This is breathtakingly astounding that science is nothing like it was centuries ago. It is important to remember that conventional science helped the modern science to set its standards.

How to Improve Your Confidence in Work Place

How to Improve Your Confidence in Work Place

Useful Tips:

Confidence is believing in yourself and in your capabilities, it means to give yourself a chance to prove your worth to the world or even to yourself sometimes. Sometimes People don’t have confidence to face themselves and question their credibility and this where lacking kicks in. Being confident is the key to successful life. Especially in a wok place. Here are some useful tips to improve your confidence at
work place.

1) Make sure to be your best motivator. First rule is always to focus on your work, once you have done you work. Go and represent it with full confidence in front of your boss. Take deep breaths. Give yourself a prep talk. It is very important to boost your confidence before any presentation. Self-confidence is very important. Prepare yourself to be best at every position.

2) Eliminate all the pessimistic things which makes you question your worth. Make sure that you surround yourself with the people who are very optimistic in nature at work and always have something good and encouraging to say to you. Being with negative people never lets you achieve bigger things in life. Never be one of negative people and always try to stay away from them.

3) Be open and ask questions and participate at work place. It is essential to participate n tiny tasks of office. Go to your boss and ask questions related to the new program. Tell them your new innovative ideas about new program, tell them you have better resource links. Tell whatever is going in your mind. Take them as your friend.

4) Always focus on your goals. Don’t hesitate to ask for promotion if you think time has come. Don’t make your promotions delayed just because of lack of confidence. If everyone is getting promoted or if you think that your promotion is promised and hasn’t been done then ask your boss. Question them. Don’t sit at one place and think that things will go your way automatically. Make the flow for yourself easy by being active.

5) Make your profile stronger. Try to make yourself up to date. Try to communicate to your clients and create connections with them. It will help you out in work as well as in future. Learn new skills from your colleagues and make your profile stronger.

6) B more productive. Try to write your schedule and make your routines that way. Do your work and as go through the schedule to see if you could’ve done that work in any better way. Evaluate your performance at work. If your boss is not happy with your confidence, think to make your work improved and just the way your boss want, by applying different and unique techniques. Surprise your boss with your intellect.

Does Technology Makes People Lonely?

Does Technology Makes People Lonely?

There was a time when people were living in the villages and having no communication devices etc. the environmental was clean and green., No cell phone, no Television, No Telephone and no other ways of communications were used. Now we cannot even imagine without such things in our daily life.

All these are the things invented by time and technology. No doubt we are making such quick and great progress in every field of life but a very big drawback of this progress is rising i.e. the peoples are using all these facilities but they are moving away from each other.
Now a person male or female both are affected by this phoenix. Many of us using android cell phone and other internet related facilities but they don’t have time to spend with their love ones. We don’t have time sit back and relax with our elders. We don’t have to spend with our kids, or parents, even some times if husband and wife both are working then they don’t have to discuss with each other their personal & kids issues. Their kids are being grown up without any parental care and morality.

Internet has an attraction in it and if a person uses it he/she may spend there hours and hours but he/she does not have few mints to spend with their loved ones. On the other hand the people who don’t uses the internet they are waiting for their loved ones give them some attention, care and love but they don’t. so we can say that the technology improvement making people lonely.

As human being we need love, care, attention and humanity but are forgetting everything and we are losing our moral values as well humanity. Remember if we are giving love, care and attention to our loved ones than we can change this scenario or else we will lose everything and we will reach a point from where we cannot reverse this situation. So we have to think about it today. I am not against progress but balanced life is requested.

Environmental Factors are the Cause Cancer

Environmental Factors are the Cause of Cancer


There are many environmental factors which are leading us towards cancer, but we will discuss here only few of them.
First of all UV factor is basically known as ultra violet rays directly from sun. Allah almighty has created this universe very beautiful our earth is a symbol of life and beauty of His own. If we create any this we must have to protect it. This rule which That Almighty has also applied for this earth. He has protected us from UV factor by creating a lyre of Ozone around the earth. Which protect us from ultra –Violet rays of sun, so that we may keep safe from Cancer and other harmful factors.

Our Environmental creating such as Carbon Mono oxide and dioxide in very large quantity. Our factories, motor vehicles, etc. are the major production of this oxide due to which this lyre of Ozone is being damaged. And is not recoverable so we are leading towards a very difficult situation.

So it is very difficult to protect ourselves from these dangerous and harmful diseases as we are making such a big progress in science and technologies but our environment is also changing.
These factors are the cause of cancer. If we have to protect the humanity then must have to make changes in our society such as town planning is first. Look at the cities having high index of air purification must have clean environment, there was no planning of clean and green peace of societies in the begging so we need to know more for these factors. Coal , Mining , Factories are the major producing of waste water and unpurified air (Pollution) due to which our humanity is suffering.

Clean and green air and pure water is our necessity and right. If we can’t control these factors we are pushing humanity toward dangerous and painful situation.

Best Way to Train your Toddlers?

Best Way to Train your Toddlers?

Toddler are babies of 12 to 36 months old. They are called toddlers because they walk unsteadily in this age group. Toddlers are developing emotional, cognitive and social behavior in this age. They don’t have any sense so it is easy for parents to train them and tell them what is wrong and right. Parents should be very attentive in this age group, they need to give extra care to the child. Toddler require all the attention because they are in learning process and to develop their sense on worldly things is very important. Moreover, some parents neglect their child and does not give basic training to them, thinking there is a lot of time for toddlers to learn.

Training toddler is hard but it is worth it, when you are in the market or at someone’s house and your child acts well behaved, you would not trade anything for that. Toddlers take time but they eventually learn.

How to train toddlers in a best ways:

  •  Discipline them:

Kids will always listen to their parents in one way or another. Some kids understand soon and some are very stubborn to understand at all. All parents need to do with stubborn kids are to make them discipline. Discipline is something that comes with hard work. You need to communicate with your child and tell them that they need to clean their play place when they are done playing because it looks dirty and is a bad habit. If they don’t understand and shrug it off, you need to be little strict and reinforce it on them.

  • Tell them “NO”:

Sometimes parents get very emotional and let their kid do whatever they want, even though they are making mess. It is very problematic and parents need to tell them

“No” if they are creating chaos. It will develop bit of fear in toddler’s heart and he will gradually accept the fact that whatever I do is wrong. There is no need to let your child spoiled because you love them. Everyone love their kids but kids get out of hands when they are not stopped from doing bad things.

  • Treat them with love:

Sometimes parent get too hard on their child and scold them all the time to make them learn difference between right and wrong or to discipline them. But, it is important to know that they are kids at the end of the day and they require your love then anyone. Don’t be harsh on them thinking this is only way to make them civil human. Some kids learn with love more than scolding.

  • Develop patience in yourself:

Being patient in this whole process as a parent is no more a battle. Sometimes parents also gets exhausted by repetitive stuff because kids could be stubborn sometimes while learning new stuff. Do remember that this process requires a lot of patience and dealing with patience is a key.

  • Toilet training:

While you train your kid for everything new, toilet training tops the deal. It is very important for a toddler to learn this. Deal with patience and tell them to notify you or call you out when there is a need for them to poop. Toddler age is the best age for them to understand them

  • Try to be consistent:

When your kid rants for pack of chips or cookies in market, tell them it’s a No, even if they create a scene in the Walmart store. You have to be consistent in making your child learn discipline and it is important to tell them that their every wrong wish won’t be fulfilled. However, if you buy your kid a pack of chips to get rid of embarrassment, beware that next time even if you say no hundred times he will want that pack of chips in any way so try to be consistent and strict about some rules.

  • It is a job of two:

Inclusion of both parent is very substantial.  Gregory Oliver, a child psychologist at the Henry Ford Health System, in Detroit says “you and your spouse also need to be on the same page when it comes to family rules”. Don’t put all the pressure on one of the partner while you spoil your child with everything and your partner is doing everything to make them disciplined. It includes both of parties not only just father or mother.

Parents need to label their house with chits in which they have mentioned letters or alphabets or new words, whatever they want their child to learn. Learning in this way is very unique and fast process. Kids identify the chits and call out the alphabets written on them. Use refrigerator or any board in which you use glue stick. Use colorful markers to write on chits and label them around house. Play games with your kid to make them better understand the vocabulary, play scavenger hunt and many more games in which their learning process is increased. Pin up pictures on walls and let your kid identify those pictures. It is a very cool act to make your kid understand between things so he will be able to differentiate between them. Use rhymes by singing them not making them watch it on television or mobile sets, but sing it to them so they adopt it from you, before they adopt it from anywhere else.

Why Phage Therapy is Better than Antibiotics?

Why Phage Therapy is Better than Antibiotics?

Phage therapy is incredible cure to antibiotic resistance.  Felix d’Herelle was the first scientist to identify the phage therapy that how its emergence can kill specific targeted bacteria and coined the word “bacteriophage” (bacteria-eater) along with Fredrick Twort. They also ran clinical treatment of phage which ended in success. It opens gate for everyone but Tbilisi in Georgia has Eliava institute that solely works in production of versatile phages and deals with different patients from all over the world, it was founded at 1933 but phage therapy was abandoned as antibiotics were discovered after World War 2.  Bacteriophages are the viruses of bacteria, composed of DNA and RNA moves around bacterium to bacterium enclosed with protein capsids.

Antimicrobial resistance is causing deaths of millions every year. Not only developing countries but also developed countries have failed to combat AMR. It has been estimated by researchers that by 2050 ten million people will be dead just because of antimicrobial resistance (AMR). Clinical trials of phage therapy tends to be noticed and given importance as a cure.

By studies it have been proved that phage therapy holds the potential to effectively control inflammation caused by disease as parallel to attacking bacteria on its target site. There are two kinds of phages one lytic phage known as virulent and another lysogenic phage known as temperate phages. Lytic phages are those which follows lytic pathway and simply destroy the cell by adhering to the bacterial cell and then penetrate nucleic acid releasing new phage component proteins, nucleic acids. Lysogenic pathway is totally different as the temperate viruses do not kill the infected host bacterial cells. Their chromosome becomes integrated into a specific section of host cell chromosome while inserting genome into host DNA, it becomes dormant and while it’s dormant virus replicates but in lytic cycle virus constantly replicates.

Lytic bacteriophage system also called holin-lysin system.  Two group of proteins are required to kill the host cell holins and endolysin. Holins synergize with endolysin and also control the time of bacterial cell lysis and endolysin does the lysis part, death of host cell. Also some lytic bacteriophages use single proteins to block the synthesis of peptidoglycan called amurins.

Alexander flemming warned us 60 years ago about antibiotic resistance and now it’s actually happening and we need to find alternative ways to treat ourselves without the help of antibiotics. Phage therapy is the best cure of this resistance, Phages are found to be approximately 10 power 7 in per ml in liquid and 10 power 9 in sediment, can be found in harsh conditions as deserts and hot springs. .

Phages are considered as natural processes because they are xenobiotics composed of nucleic acids and amino acids entirely unlike antibiotics. Phage developing procedure is cheaper than antibiotics and effective against multi drug resistant pathogenic bacteria. Phages are very target oriented, so firstly it is important to diagnose infection in bacteria contrary with antibiotics where they had a broad range of target and mostly treat undiagnosed bacterial infection.  Most of the threatening diseases does not have ultimate cure, so patients are on antibiotics for lifetime but phage therapy treatment includes reduced dosages because of its self-replicative nature. Furthermore, custom treatments are also available in phage therapies for some hard to treat bacterial diseases. Sometimes the dosages which work in vitro does not work in vivo so potentially strong phages are required to treat the effect in live host than in cell culture.

Due to the presence of antibiotic resistance mutation, it has been proposed that bacteria can also be resistant against phages but phages are host specific and they evolve as bacteria evolves and sometimes even stronger than bacteria so bacterial resistance is not a problem for phages. Phage therapy are hard to patent due to being natural discovery so that is why many pharmaceutical companies shows very confined interest in phages and funding is difficult to gather for this type of research. Phages are licensed to be used in food processing industry to reduce the use of antibiotics and likewise phage Listeria sp., targets the foodborne pathogen is used in dairy industry.

Why Phage Therapy is better than Antibiotics; facts:

Phage therapy have many unique advantage over antibiotics. The most interesting thing in it is that as bacteria evolve resistance, relevant phages also evolve resistance alongside. When bacterium appears, phage already attacks it. Phages penetrate deeper as the infection is unlike like antibiotics, which decrease in concentration.

  • Bacteriophages are very site specific, only attack on targeted site, no secondary infections occur
  • Replicate at the site of infection unlike antibiotics
  • There are no side effects present of phage therapy
  • Selecting new phage is work of two weeks while synthesizing new antibiotic takes a lot of time.
  • Phage therapy costs $2,500 in Georgia

Antibiotics are lethal and we have to reach for better options. In 2016, a woman died because of bacterial infection. People are dying because of bacterial diseases and antibiotics are useless as bacteria have become stronger. It takes approximately 10 years for scientist to make new antibiotic for specific disease and get the FDA approval. Bacteriophage is the solution to all of this chaos; which infect virus and then kills it. Phages are able to kill antibiotic resistant bacteria. Phage makes a lot of holes inside bacteria and destroy, kill it completely